EFEMP2 and ZNF638

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		EFEMP2	ZNF638
Description		EGF containing fibulin extracellular matrix protein 2	zinc finger protein 638
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GO Annotations	Cellular Component	Extracellular Region Basement Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding	Double-stranded DNA Binding RNA Binding Zinc Ion Binding
	Biological Process	Elastic Fiber Assembly	RNA Splicing
Pathways		Molecules associated with elastic fibres Molecules associated with elastic fibres	Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases		Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS		Acne (severe) ( 24927181) Birth weight ( 31043758)	Cognitive ability ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Heel bone mineral density ( 30598549 28869591) Height ( 25282103 25429064 31562340 23456168) Hip circumference adjusted for BMI ( 28552196) Intelligence ( 28530673) Pulse pressure ( 27841878 30578418) QRS interval (sulfonylurea treatment interaction) ( 27958378) Reaction time ( 29844566) Testicular germ cell tumor ( 28604728)
Interacting Genes		52 interacting genes: AMMECR1 APEX2 AQP1 ATN1 ATXN1 ATXN7 BAG6 C5orf24 CACNA1A CATSPER1 CCDC33 CCND3 CCNK COL8A1 CREB5 DGCR6 FAM107A FAM124B FAM74A4 GFI1B GLRX3 HDAC4 HHEX HOXA1 IL16 LCE2D LCE3C LINGO1 MEOX2 NEDD4L NOS3 NUFIP2 PIDD1 PLSCR1 PLSCR4 PRPF31 PTGER3 RBPMS RERE RHOXF2 RHPN1 RIBC2 SGTA SGTB STK16 TCAF1 TP53 UBQLN1 UBQLN4 ZNF263 ZNF426 ZNF638	13 interacting genes: CALCOCO2 CCDC85B EFEMP2 FHL2 HOOK2 KIFBP KRT15 KRT19 KRTAP4-12 NELFCD PLSCR1 SPP1 WWP1
Entrez ID		30008	27332
HPRD ID		05221	11736
Ensembl ID		ENSG00000172638	ENSG00000075292
Uniprot IDs		A0A024R5G1 O95967 Q9H3D5	A8K583 Q14966
PDB IDs		2KL7	6SXW
Enriched GO Terms of Interacting Partners?
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