MEOX1 and UBE2R2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MEOX1	UBE2R2
Description		mesenchyme homeobox 1	ubiquitin conjugating enzyme E2 R2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm	Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Molecular_function Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Somite Specification Multicellular Organism Development Biological_process Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	Protein Monoubiquitination Protein Ubiquitination Protein K48-linked Ubiquitination
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Fractures ( 30158200)	Bipolar disorder ( 20351715) Body mass index ( 25673413) Estimated glomerular filtration rate ( 31015462) Health literacy ( 31250787)
Interacting Genes		33 interacting genes: ACBD4 ALOX5 APP APPL1 BANP CIAO1 CIB3 CKS1B CWF19L2 CYFIP1 DCX FMR1 LMNA MAPK9 MEF2A MID1 MORF4L1 MVP NAGK NEIL2 PAGE3 PAX1 PAX3 PRKN QRICH1 RANBP3 RBM5 SOX10 SYT17 TCEANC TXLNA UBE2R2 UBXN2B	25 interacting genes: APPBP2 ARHGDIA ARIH2 BTRC CBLC CSNK2A1 CSNK2A2 CTNNB1 CUL3 DTX3L DZIP3 FBXW5 INF2 ITCH MAEA MDM2 MEOX1 MUL1 PNPLA2 PRKN RBX1 RNF113B RNF31 UBA1 UBC
Entrez ID		4222	54926
HPRD ID		02537	15602
Ensembl ID		ENSG00000005102	ENSG00000107341
Uniprot IDs		P50221	Q712K3
PDB IDs			6NYO
Enriched GO Terms of Interacting Partners?
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