MEOX1 and CYFIP1

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		MEOX1	CYFIP1
Description		mesenchyme homeobox 1	cytoplasmic FMR1 interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm	Ruffle Extracellular Region Cytosol MRNA Cap Binding Complex Focal Adhesion Lamellipodium SCAR Complex Filopodium Tip Secretory Granule Lumen Specific Granule Lumen Neuron Projection Neuronal Cell Body Terminal Bouton Dendritic Spine Dendritic Growth Cone Axonal Growth Cone Synapse Perinuclear Region Of Cytoplasm Excitatory Synapse Extracellular Exosome Central Region Of Growth Cone Peripheral Region Of Growth Cone Tertiary Granule Lumen
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Molecular_function Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding	RNA 7-methylguanosine Cap Binding Protein Binding Translation Regulator Activity Rac GTPase Binding Actin Filament Binding
	Biological Process	Somite Specification Multicellular Organism Development Biological_process Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	Cell Morphogenesis Regulation Of Translation Axon Guidance Regulation Of Cell Shape Rac Protein Signal Transduction Cell Projection Assembly Lamellipodium Assembly Ruffle Organization Cellular Response To Insulin Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Neutrophil Degranulation Positive Regulation Of Axon Extension Vascular Endothelial Growth Factor Receptor Signaling Pathway Axon Extension Cognition Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway Response To Electrical Stimulus Dendrite Extension Modification Of Synaptic Structure Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Positive Regulation Of Dendrite Development Positive Regulation Of Ruffle Assembly Negative Regulation Of Synaptic Vesicle Recycling Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Neutrophil degranulation FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Fractures ( 30158200)	Heel bone mineral density ( 30598549) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		33 interacting genes: ACBD4 ALOX5 APP APPL1 BANP CIAO1 CIB3 CKS1B CWF19L2 CYFIP1 DCX FMR1 LMNA MAPK9 MEF2A MID1 MORF4L1 MVP NAGK NEIL2 PAGE3 PAX1 PAX3 PRKN QRICH1 RANBP3 RBM5 SOX10 SYT17 TCEANC TXLNA UBE2R2 UBXN2B	19 interacting genes: ACTA1 APBB1 EFHC2 EFTUD2 FMR1 FXR2 GAS7 GNB1 MEOX1 MYO16 NUP98 NYAP1 NYAP2 PPP1CC PRPF40A RAC1 RFX6 SCTR TCERG1
Entrez ID		4222	23191
HPRD ID		02537	05890
Ensembl ID		ENSG00000005102	ENSG00000273749
Uniprot IDs		P50221	Q7L576
PDB IDs			3P8C 4N78
Enriched GO Terms of Interacting Partners?
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