MEOX1 and RBM5

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		MEOX1	RBM5
Description		mesenchyme homeobox 1	RNA binding motif protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm	Nucleus Nucleoplasm Spliceosomal Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Molecular_function Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding	DNA Binding RNA Binding MRNA Binding Protein Binding Metal Ion Binding
	Biological Process	Somite Specification Multicellular Organism Development Biological_process Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	Spliceosomal Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Fractures ( 30158200)	Age at first birth ( 27798627) Blood protein levels ( 28240269) Body mass index ( 26426971) Dentures ( 31235808) Extremely high intelligence ( 29520040) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549) Morning person ( 30696823) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Regular attendance at a gym or sports club ( 29970889) Sleep duration (short sleep) ( 30846698)
Interacting Genes		33 interacting genes: ACBD4 ALOX5 APP APPL1 BANP CIAO1 CIB3 CKS1B CWF19L2 CYFIP1 DCX FMR1 LMNA MAPK9 MEF2A MID1 MORF4L1 MVP NAGK NEIL2 PAGE3 PAX1 PAX3 PRKN QRICH1 RANBP3 RBM5 SOX10 SYT17 TCEANC TXLNA UBE2R2 UBXN2B	22 interacting genes: BCL2L1 CASK DCX DDX17 GAPDH ILF3 KIF19 KIF9 LIG4 LRIF1 LSM8 MED1 MEOX1 MEOX2 NDEL1 PARD3B PCM1 PKP2 RBM14 WBP11 WDR77 ZDHHC17
Entrez ID		4222	10181
HPRD ID		02537	06052
Ensembl ID		ENSG00000005102	ENSG00000003756
Uniprot IDs		P50221	A0A024R2U6 P52756
PDB IDs			2LK0 2LK1 2LKZ 5MF9 5MFY
Enriched GO Terms of Interacting Partners?
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