SMAD1 and ARHGEF6

  • Number of citations of the paper that reports this interaction (PubMedID 15761153)
  • 246
  • Data Source:
  • HPRD (in vivo)

SMAD1

ARHGEF6

Description SMAD family member 1 Rac/Cdc42 guanine nucleotide exchange factor 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Lung function (FEV1) ( 30061609)
  • Midgestational cytokine/chemokine levels (maternal genetic effect) ( 30134952)
  • Panic disorder ( 31712720)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes 142 interacting genes: ACVR1 ACVRL1 AKR1B1 ANKRD27 AP2A2 APP AR ARHGEF6 ARL4D BMPR1A BTBD2 BTG2 CAMSAP1 CDK7 CDK9 CHMP3 CILK1 COL4A1 DACH1 DNMT3L DVL1 ECSIT EIF2AK4 ELP3 EP300 ERBIN EWSR1 FBXL12 FBXO30 FHL5 FOXG1 FRZB GDF6 GLI3 GMEB1 GSC HBP1 HIPK2 HOXA13 HOXA5 HOXC8 HOXD13 ING2 INPP4A IRF2BP1 KAT2B KMT2D LEF1 LEMD3 LMNA MAP2K3 MAPK1 MAST4 MBD1 MECOM MED6 MEN1 MGA MRTFB NAT9 NEDD4 NEDD9 NEUROG1 NKX3-2 NOTCH2 OAZ1 OAZ3 PAK1 PARD3 PIAS1 PIAS4 PIGQ PLEKHB1 PREB PSMB4 PSMD1 PSMD11 PUM1 RAB2B RAB30 RAB34 RAB38 RAB3B RAB6B RAC2 RAN RAP2A RASD2 RASL12 RFX1 RHEBL1 RHOG RPS27A SF3B1 SKI SKIL SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMARCE1 SMURF1 SMURF2 SNIP1 SNRNP70 SOX5 SQSTM1 SS18L1 STARD13 STK11 STUB1 SUV39H1 TCF20 TGFBR1 TNNT1 TOB1 TRIP6 TTF1 TTF2 UBA52 UBC UBE2Z UBXN1 USP45 VEPH1 WDR77 XPC XPO1 YAP1 YY1 ZBTB44 ZDHHC3 ZEB2 ZNF251 ZNF423 ZNF510 ZNF512B ZNF521 ZNF76 ZNF8 ZSCAN4 24 interacting genes: ADAM15 ARAP3 ARHGEF7 BMPR1B CAPNS1 CDC42 EPHB2 GIT1 GPRASP2 PAK1 PAK2 PAK3 PARVB SH2D1A SH3GL3 SIRPA SMAD1 SMAD2 SMAD3 TGFBR1 TGFBR2 TMEM108 YWHAG ZNF580
Entrez ID 4086 9459
HPRD ID 03356 02226
Ensembl ID ENSG00000170365 ENSG00000129675
Uniprot IDs Q15797 B7Z3C7 Q15052 Q8N4Q3
PDB IDs 1KHU 2LAW 2LAX 2LAY 2LAZ 2LB0 2LB1 3Q47 3Q4A 5ZOK 1UJY 1WYR
Enriched GO Terms of Interacting Partners?
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