KRT8 and WBP2

Number of citations of the paper that reports this interaction (PubMedID 27578003)
17

Data Source:
BioGRID (pull down)

		KRT8	WBP2
Description		keratin 8	WW domain binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Estrogen Receptor Binding Chromatin DNA Binding
	Biological Process	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process	Response To Progesterone Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen Establishment Of Protein Localization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Progesterone Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Positive Regulation Of Histone H3-K14 Acetylation
Pathways		Keratinization Formation of the cornified envelope
Drugs		Tenecteplase Copper
Diseases
GWAS		Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Prostate cancer ( 21743057)
Interacting Genes		35 interacting genes: ANXA1 BYSL CLK1 DEDD DMD EGFR ELOC ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT18 KRT31 KRT38 KRT40 MAPK1 MAPK14 MAPK3 MAPK8 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 TCHP TFIP11 TROAP WBP2	47 interacting genes: ANAPC1 ANKRD13A ANKRD13D ARCN1 CLEC4G COPA COPB1 COPB2 COPE COPG1 CUEDC1 DDX17 EEF1B2 EPN2 ESR1 GRPEL1 H4C1 HUWE1 ITCH KRT18 KRT8 KRT9 MAGEA4 MAGI1 MYO6 NEDD4 NEDD4L PAX8 POLH RHBDD3 RNF168 RPS27A RPS3 SDHA SEPTIN3 TDP2 TOLLIP TOM1L2 UBA52 UBC UBE3A UBQLN1 UIMC1 WWP1 WWP2 WWTR1 YAP1
Entrez ID		3856	23558
HPRD ID		01015	06097
Ensembl ID		ENSG00000170421	ENSG00000132471
Uniprot IDs		P05787 Q7L4M3	A0A024R8L1 Q969T9
PDB IDs
Enriched GO Terms of Interacting Partners?
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