WBP2 and RPS3

Number of citations of the paper that reports this interaction (PubMedID 27578003)
17

Data Source:
BioGRID (pull down)

		WBP2	RPS3
Description		WW domain binding protein 2	ribosomal protein S3
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrial Inner Membrane Mitochondrial Matrix Endoplasmic Reticulum Cytosol Ribosome Polysome Plasma Membrane Focal Adhesion Postsynaptic Density Membrane Cytosolic Small Ribosomal Subunit Ruffle Membrane Extracellular Exosome NF-kappaB Complex Mitotic Spindle Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Estrogen Receptor Binding Chromatin DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA Binding Damaged DNA Binding RNA Binding MRNA Binding Structural Constituent Of Ribosome DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Endodeoxyribonuclease Activity Protein Binding Microtubule Binding Transcription Factor Binding Tubulin Binding DNA N-glycosylase Activity Enzyme Binding Kinase Binding Protein Kinase Binding Hsp70 Protein Binding Oxidized Purine DNA Binding Oxidized Pyrimidine DNA Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein-containing Complex Binding Protein Kinase A Binding Iron-sulfur Cluster Binding Hsp90 Protein Binding Small Ribosomal Subunit RRNA Binding Supercoiled DNA Binding Class I DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity
	Biological Process	Response To Progesterone Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen Establishment Of Protein Localization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Progesterone Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Positive Regulation Of Histone H3-K14 Acetylation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay DNA Repair Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Apoptotic Process Cellular Response To DNA Damage Stimulus Response To Oxidative Stress Chromosome Segregation Positive Regulation Of Gene Expression Negative Regulation Of Translation Viral Transcription Positive Regulation Of Microtubule Polymerization Positive Regulation Of Protein Complex Assembly Negative Regulation Of Protein Ubiquitination Positive Regulation Of Endodeoxyribonuclease Activity Positive Regulation Of Interleukin-2 Production Positive Regulation Of Activated T Cell Proliferation DNA Damage Response, Detection Of DNA Damage Regulation Of Apoptotic Process Positive Regulation Of JUN Kinase Activity Negative Regulation Of DNA Repair Positive Regulation Of DNA Repair Positive Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Spindle Assembly Cell Division Response To TNF Agonist Cellular Response To Hydrogen Peroxide Cellular Response To Tumor Necrosis Factor Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of DNA N-glycosylase Activity Positive Regulation Of Base-excision Repair Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Interacting Genes		47 interacting genes: ANAPC1 ANKRD13A ANKRD13D ARCN1 CLEC4G COPA COPB1 COPB2 COPE COPG1 CUEDC1 DDX17 EEF1B2 EPN2 ESR1 GRPEL1 H4C1 HUWE1 ITCH KRT18 KRT8 KRT9 MAGEA4 MAGI1 MYO6 NEDD4 NEDD4L PAX8 POLH RHBDD3 RNF168 RPS27A RPS3 SDHA SEPTIN3 TDP2 TOLLIP TOM1L2 UBA52 UBC UBE3A UBQLN1 UIMC1 WWP1 WWP2 WWTR1 YAP1	18 interacting genes: ATP6V0D2 CCT2 CSNK2A1 DDIT3 FOLH1 HSP90AA1 IL7R MDM2 NDRG1 NFKB1 PTEN RELA RPL9 SUMO1 TP53 UBC WBP2 YWHAQ
Entrez ID		23558	6188
HPRD ID		06097	10941
Ensembl ID		ENSG00000132471	ENSG00000149273
Uniprot IDs		A0A024R8L1 Q969T9	P23396
PDB IDs			1WH9 4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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