KRT8 and PNN

Number of citations of the paper that reports this interaction (PubMedID 10809736)
9

Data Source:
HPRD (in vitro, two hybrid)

		KRT8	PNN
Description		keratin 8	pinin, desmosome associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Intermediate Filament Plasma Membrane Cell-cell Junction Membrane Nuclear Speck Desmosome Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding	DNA Binding RNA Binding Structural Molecule Activity Protein Binding
	Biological Process	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process	MRNA Splicing, Via Spliceosome Cell Adhesion
Pathways		Keratinization Formation of the cornified envelope
Drugs		Tenecteplase Copper
Diseases
GWAS		Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Prostate cancer ( 21743057)
Interacting Genes		35 interacting genes: ANXA1 BYSL CLK1 DEDD DMD EGFR ELOC ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT18 KRT31 KRT38 KRT40 MAPK1 MAPK14 MAPK3 MAPK8 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 TCHP TFIP11 TROAP WBP2	17 interacting genes: CNGB1 CSNK2A1 CTBP1 CTBP2 DYNC1I2 KRT18 KRT19 KRT8 PNISR PPIG PRPF4B RNPS1 SRPK2 SRRM2 SRSF4 YWHAG ZCCHC17
Entrez ID		3856	5411
HPRD ID		01015	04401
Ensembl ID		ENSG00000170421	ENSG00000100941
Uniprot IDs		P05787 Q7L4M3	Q9H307
PDB IDs
Enriched GO Terms of Interacting Partners?
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