KRT8 and TCHP

Number of citations of the paper that reports this interaction (PubMedID 15731013)
22

Data Source:
HPRD (two hybrid)

		KRT8	TCHP
Description		keratin 8	trichoplein keratin filament binding
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Desmosome Keratin Filament Apical Cortex Ciliary Transition Fiber
	Molecular Function	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding	Protein Binding
	Biological Process	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly
Pathways		Keratinization Formation of the cornified envelope
Drugs		Tenecteplase Copper
Diseases
GWAS		Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Prostate cancer ( 21743057)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		35 interacting genes: ANXA1 BYSL CLK1 DEDD DMD EGFR ELOC ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT18 KRT31 KRT38 KRT40 MAPK1 MAPK14 MAPK3 MAPK8 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 TCHP TFIP11 TROAP WBP2	23 interacting genes: CCDC172 CCDC85B CDR2 DYDC1 IFFO1 KCTD17 KRT14 KRT15 KRT16 KRT18 KRT40 KRT5 KRT6A KRT8 LZTS2 MIPOL1 MKRN3 NAB2 NDOR1 NME7 TEX11 TRIM27 VIM
Entrez ID		3856	84260
HPRD ID		01015	14403
Ensembl ID		ENSG00000170421	ENSG00000139437
Uniprot IDs		P05787 Q7L4M3	A0A024RBM9 Q9BT92
PDB IDs
Enriched GO Terms of Interacting Partners?
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