WBP2 and POLH

Number of citations of the paper that reports this interaction (PubMedID 27578003)
17

Data Source:
BioGRID (two hybrid)

		WBP2	POLH
Description		WW domain binding protein 2	DNA polymerase eta
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm	Nucleus Nucleoplasm Replication Fork Cytosol Site Of Double-strand Break
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Estrogen Receptor Binding Chromatin DNA Binding	Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Metal Ion Binding
	Biological Process	Response To Progesterone Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen Establishment Of Protein Localization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Progesterone Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Positive Regulation Of Histone H3-K14 Acetylation	DNA Synthesis Involved In DNA Repair DNA Replication DNA Repair Regulation Of DNA Repair Pyrimidine Dimer Repair Response To Radiation Response To UV-C Translesion Synthesis Error-prone Translesion Synthesis Error-free Translesion Synthesis Cellular Response To UV-C
Pathways			Translesion Synthesis by POLH Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR)
Drugs
Diseases			Disorders of nucleotide excision repair, including: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); UV-sensitive syndrome (UVS); Trichothiodystrophy (TTD); Cerebro-oculo-facio-skeletal syndrome (COFS); XFE progeroid syndrome
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		47 interacting genes: ANAPC1 ANKRD13A ANKRD13D ARCN1 CLEC4G COPA COPB1 COPB2 COPE COPG1 CUEDC1 DDX17 EEF1B2 EPN2 ESR1 GRPEL1 H4C1 HUWE1 ITCH KRT18 KRT8 KRT9 MAGEA4 MAGI1 MYO6 NEDD4 NEDD4L PAX8 POLH RHBDD3 RNF168 RPS27A RPS3 SDHA SEPTIN3 TDP2 TOLLIP TOM1L2 UBA52 UBC UBE3A UBQLN1 UIMC1 WWP1 WWP2 WWTR1 YAP1	9 interacting genes: APP DYNLL1 PCNA POLD2 POLI REV1 RPS27A USP7 WBP2
Entrez ID		23558	5429
HPRD ID		06097	04913
Ensembl ID		ENSG00000132471	ENSG00000170734
Uniprot IDs		A0A024R8L1 Q969T9	A0A024RD62 B3KN75 B4DG64 Q9Y253
PDB IDs			2I5O 2LSK 3JAA 3MR2 3MR3 3MR5 3MR6 3SI8 3TQ1 3WUP 4DL2 4DL3 4DL4 4DL5 4DL6 4DL7 4ECQ 4ECR 4ECS 4ECT 4ECU 4ECV 4ECW 4ECX 4ECY 4ECZ 4ED0 4ED1 4ED2 4ED3 4ED6 4ED7 4ED8 4EEY 4J9K 4J9L 4J9M 4J9N 4J9O 4J9P 4J9Q 4J9R 4J9S 4O3N 4O3O 4O3P 4O3Q 4O3R 4O3S 4Q8E 4Q8F 4RNM 4RNN 4RNO 4RU9 4YP3 4YQW 4YR0 4YR2 4YR3 5DG7 5DG8 5DG9 5DGA 5DGB 5DLF 5DLG 5DQG 5DQH 5DQI 5EWE 5EWF 5EWG 5F9L 5F9N 5JUM 5KFA 5KFB 5KFC 5KFD 5KFE 5KFF 5KFG 5KFH 5KFI 5KFJ 5KFK 5KFL 5KFM 5KFN 5KFO 5KFP 5KFQ 5KFR 5KFS 5KFT 5KFU 5KFV 5KFW 5KFX 5KFY 5KFZ 5KG0 5KG1 5KG2 5KG3 5KG4 5KG5 5KG6 5KG7 5L1I 5L1J 5L1K 5L1L 5L9X 6D0M 6D0Z 6M7O 6M7P 6M7T 6M7U 6M7V 6MP3 6MQ8 6MXO 6PZ3 6Q02
Enriched GO Terms of Interacting Partners?
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