RUNX1T1 and CPSF7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RUNX1T1	CPSF7
Description		RUNX1 partner transcriptional co-repressor 1	cleavage and polyadenylation specific factor 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Matrix	Nucleus Nucleoplasm Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly
Pathways			mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases		Acute myeloid leukemia (AML)
GWAS		Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Number of sexual partners ( 30643258) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Plasma anti-thyroglobulin levels ( 29678681) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		52 interacting genes: ABI3 ATN1 BCL6 BRCA1 C19orf57 CBFA2T3 CBY2 CEP170P1 CPSF7 CREB3L1 DNMT1 EFHC2 EPS8 ETS1 GFI1 GSE1 HDAC1 HDAC3 HDAC8 HOMER3 HSP90AA1 ID1 ID3 IHO1 KPNA1 KPNB1 LPXN LZTS2 MEOX2 MID2 NCOR1 NCOR2 NECAB2 NEUROG1 PCBD2 PRKAR2A SIN3A SPEN SPRY2 STX11 TAF9B TAL2 TCF12 TCF3 TCF4 TRIM42 UBQLN4 VDR WBP11 ZBTB16 ZMYM4 ZNF652	25 interacting genes: APBB1 ARMC7 ATXN1 CCDC86 CLK2 CSNK2A1 DVL2 EPM2AIP1 EWSR1 GCC1 ITCH NCK2 NUDT21 PRMT2 RBM10 RUNX1T1 SEC23B SMAD3 SNRNP25 SORBS3 SRPK2 TLE5 U2AF2 WBP4 WWOX
Entrez ID		862	79869
HPRD ID		00590	16906
Ensembl ID		ENSG00000079102	ENSG00000149532
Uniprot IDs		A0A087WWT6 A0A0A0MSU1 B2R6I9 Q06455 W8FW32	B4DGF8 Q8N684
PDB IDs		1WQ6 2DJ8 2H7B 2KNH 2KYG 2OD1 2ODD 2PP4 4JOL	3N9U
Enriched GO Terms of Interacting Partners?
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