HOXB6 and CLK3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HOXB6	CLK3
Description		homeobox B6	CDC like kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Acrosomal Vesicle Nucleus Nucleoplasm Membrane Nuclear Speck Intermediate Filament Cytoskeleton
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Binding Protein Binding	RNA Binding Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Erythrocyte Homeostasis Embryonic Skeletal System Morphogenesis	Protein Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation
Pathways
Drugs			5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
Diseases
GWAS		Childhood body mass index ( 26604143)	Bladder cancer ( 25281661) Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941) Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Celiac disease ( 22057235) Craniofacial microsomia ( 26853712)
Interacting Genes		12 interacting genes: ALX4 CLK3 CREBBP CSNK2B EP300 HOXB7 KRT15 PKNOX1 PLSCR1 SAT1 TCEAL1 TCF21	19 interacting genes: APP CLK2 HOXB6 HOXB7 KRTAP10-3 NEDD4 OAS2 PRMT5 RBMX RBMY1A1 RBMY1F RSRP1 SDCBP SLAMF7 SRPK2 SUV39H1 TINF2 YWHAG ZNF263
Entrez ID		3216	1198
HPRD ID		00849	04290
Ensembl ID		ENSG00000108511	ENSG00000179335
Uniprot IDs		P17509	B3KRI8 P49761
PDB IDs			2EU9 2EXE 2WU6 2WU7 3RAW 6FT7 6FYP 6FYR 6KHF 6RCT
Enriched GO Terms of Interacting Partners?
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