CLK3 and SLAMF7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CLK3	SLAMF7
Description		CDC like kinase 3	SLAM family member 7
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Nucleoplasm Membrane Nuclear Speck Intermediate Filament Cytoskeleton	Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding	Identical Protein Binding
	Biological Process	Protein Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation	Adaptive Immune Response Cell Adhesion Natural Killer Cell Activation Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate	Elotuzumab
Diseases
GWAS		Bladder cancer ( 25281661) Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941) Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Celiac disease ( 22057235) Craniofacial microsomia ( 26853712)	Blood protein levels ( 30072576 29875488 28240269) IgM levels ( 28628107) Inflammatory bowel disease ( 23128233) Microalbuminuria ( 26631737) Multiple sclerosis ( 24076602)
Interacting Genes		19 interacting genes: APP CLK2 HOXB6 HOXB7 KRTAP10-3 NEDD4 OAS2 PRMT5 RBMX RBMY1A1 RBMY1F RSRP1 SDCBP SLAMF7 SRPK2 SUV39H1 TINF2 YWHAG ZNF263	4 interacting genes: CLK3 MAK SH2D1A TRIB2
Entrez ID		1198	57823
HPRD ID		04290	09432
Ensembl ID		ENSG00000179335	ENSG00000026751
Uniprot IDs		B3KRI8 P49761	B4DVL7 B4DW98 Q9NQ25
PDB IDs		2EU9 2EXE 2WU6 2WU7 3RAW 6FT7 6FYP 6FYR 6KHF 6RCT
Enriched GO Terms of Interacting Partners?
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