CLK3 and RBMY1A1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CLK3	RBMY1A1
Description		CDC like kinase 3	RNA binding motif protein Y-linked family 1 member A1
Image
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Nucleoplasm Membrane Nuclear Speck Intermediate Filament Cytoskeleton	Nucleus Nuclear Speck
	Molecular Function	RNA Binding Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Protein Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Cis Splicing, Via Spliceosome
Pathways
Drugs		5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
Diseases
GWAS		Bladder cancer ( 25281661) Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941) Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Celiac disease ( 22057235) Craniofacial microsomia ( 26853712)
Interacting Genes		19 interacting genes: APP CLK2 HOXB6 HOXB7 KRTAP10-3 NEDD4 OAS2 PRMT5 RBMX RBMY1A1 RBMY1F RSRP1 SDCBP SLAMF7 SRPK2 SUV39H1 TINF2 YWHAG ZNF263	19 interacting genes: AEN APOBEC3C CBX2 CIRBP CLK3 DAAM2 HNRNPK KHDRBS3 LNX1 PCDHB14 PRPF31 PRR3 RBM3 RBMX SRSF3 SRSF9 TERF1 TRA2B ZNF317
Entrez ID		1198	5940
HPRD ID		04290	02450
Ensembl ID		ENSG00000179335	ENSG00000234414
Uniprot IDs		B3KRI8 P49761	P0DJD3
PDB IDs		2EU9 2EXE 2WU6 2WU7 3RAW 6FT7 6FYP 6FYR 6KHF 6RCT	2FY1
Enriched GO Terms of Interacting Partners?
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