HOXB6 and ALX4

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		HOXB6	ALX4
Description		homeobox B6	ALX homeobox 4
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Binding Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding HMG Box Domain Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Erythrocyte Homeostasis Embryonic Skeletal System Morphogenesis	Skeletal System Development Hair Follicle Development Muscle Organ Development Post-embryonic Development Anterior/posterior Pattern Specification Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Embryonic Digit Morphogenesis Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Digestive Tract Development Embryonic Skeletal System Morphogenesis Roof Of Mouth Development
Pathways
Drugs
Diseases			Frontonasal dysplasia Enlarged parietal foramina/cranium bifidum
GWAS		Childhood body mass index ( 26604143)	Blood pressure measurement (high sodium intervention) ( 24165912) Cadmium levels ( 26025379) Excessive hairiness ( 29895819) Gout ( 22179738) Male-pattern baldness ( 29146897 27182965) Monobrow ( 27182965) Response to antidepressants in depression ( 29998114) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)
Interacting Genes		12 interacting genes: ALX4 CLK3 CREBBP CSNK2B EP300 HOXB7 KRT15 PKNOX1 PLSCR1 SAT1 TCEAL1 TCF21	12 interacting genes: ALX1 CEBPE EMX1 FOXA3 GATA4 HOXA3 HOXB13 HOXB6 HOXD3 LEF1 SOX10 SOX2
Entrez ID		3216	60529
HPRD ID		00849	05661
Ensembl ID		ENSG00000108511	ENSG00000052850
Uniprot IDs		P17509	Q9H161
PDB IDs			2M0C
Enriched GO Terms of Interacting Partners?
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