TLX2 and POU2F1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		TLX2	POU2F1
Description		T cell leukemia homeobox 2	POU class 2 homeobox 1
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GO Annotations	Cellular Component	Nuclear Chromatin Cellular_component Cytoplasm	Nuclear Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Intracellular Membrane-bounded Organelle RNA Polymerase II Transcription Factor Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Mesoderm Formation Positive Regulation Of Transcription By RNA Polymerase II Enteric Nervous System Development Negative Regulation Of Dendrite Morphogenesis	Cytokine-mediated Signaling Pathway Cell Differentiation SnRNA Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Interleukin-4 and Interleukin-13 signaling RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter Estrogen-dependent gene expression
Drugs
Diseases
GWAS			Asthma ( 31619474) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Diastolic blood pressure ( 30224653) Liver enzyme levels ( 18940312) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		9 interacting genes: GTF2A1L IRF6 IRF9 MCM4 MEIS1 POU2F1 TLE1 YWHAH ZNF502	49 interacting genes: APP AR BARD1 BRCA1 CEBPE CREB1 ESR1 FDXR HCFC1 HMGA1 HMGB2 HNF1A HOXB13 HOXC9 IRF9 LIFR MNAT1 MSX1 NCOR2 NFYA NPAT NR3C1 PARP1 PBX1 PGR PKNOX1 PLK3 POGZ POU2AF1 PRKACA PRKDC RARA RELA RXRA SNAPC4 SOX2 SP1 SP4 STAT5A STAT5B TBP THRA TLE4 TLE5 TLX2 TNF TXNRD1 VDR XRCC6
Entrez ID		3196	5451
HPRD ID		07254	01250
Ensembl ID		ENSG00000115297	ENSG00000143190
Uniprot IDs		O43763	A0A024R8Y2 P14859
PDB IDs		3A03	1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU
Enriched GO Terms of Interacting Partners?
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