HNRNPL and PJA1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		HNRNPL	PJA1
Description		heterogeneous nuclear ribonucleoprotein L	praja ring finger ubiquitin ligase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Ribonucleoprotein Granule Pronucleus Perinuclear Region Of Cytoplasm Extracellular Exosome Ribonucleoprotein Complex	Cytoplasm
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Transcription Regulatory Region DNA Binding Pre-mRNA Intronic Binding MRNA CDS Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing Regulation Of Translation Circadian Rhythm RNA Metabolic Process Cellular Response To Amino Acid Starvation Regulation Of RNA Splicing Positive Regulation Of Translation Negative Regulation Of MRNA Splicing, Via Spliceosome Response To Peptide Positive Regulation Of MRNA Binding	Protein Ubiquitination Protein Catabolic Process
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Copper
Diseases
GWAS		Anti-saccade response ( 29064472) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)	Birth weight ( 31043758) Body mass index ( 29273807) Schizophrenia ( 25056061 29483656)
Interacting Genes		16 interacting genes: APEX1 CSE1L CSNK2A1 FGFR3 H3-4 HMG20B HMGA1 HNRNPA2B1 HNRNPK IL7R ITCH NEDD4 PCBP2 PJA1 PTBP1 SUMO4	64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440
Entrez ID		3191	64219
HPRD ID		04360	02335
Ensembl ID		ENSG00000104824	ENSG00000181191
Uniprot IDs		P14866 Q6NTA2	Q8NG27
PDB IDs		3R27 3TO8	2L0B
Enriched GO Terms of Interacting Partners?
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