HNRNPL and PCBP2

Number of citations of the paper that reports this interaction (PubMedID 10772858)
61

Data Source:
BioGRID (pull down, pull down)
HPRD (in vitro, two hybrid)

		HNRNPL	PCBP2
Description		heterogeneous nuclear ribonucleoprotein L	poly(rC) binding protein 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Ribonucleoprotein Granule Pronucleus Perinuclear Region Of Cytoplasm Extracellular Exosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Membrane Extracellular Exosome
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Transcription Regulatory Region DNA Binding Pre-mRNA Intronic Binding MRNA CDS Binding	RNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding C-rich Single-stranded DNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing Regulation Of Translation Circadian Rhythm RNA Metabolic Process Cellular Response To Amino Acid Starvation Regulation Of RNA Splicing Positive Regulation Of Translation Negative Regulation Of MRNA Splicing, Via Spliceosome Response To Peptide Positive Regulation Of MRNA Binding	MRNA Splicing, Via Spliceosome RNA Metabolic Process MRNA Metabolic Process Negative Regulation Of Type I Interferon Production Viral RNA Genome Replication Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Negative Regulation Of Defense Response To Virus Defense Response To Virus IRES-dependent Viral Translational Initiation
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Negative regulators of DDX58/IFIH1 signaling
Drugs		Copper
Diseases
GWAS		Anti-saccade response ( 29064472) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)	Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		16 interacting genes: APEX1 CSE1L CSNK2A1 FGFR3 H3-4 HMG20B HMGA1 HNRNPA2B1 HNRNPK IL7R ITCH NEDD4 PCBP2 PJA1 PTBP1 SUMO4	27 interacting genes: BARD1 CASK CNBP FLNA FTH1 HMGA1 HMGA2 HNRNPD HNRNPK HNRNPL NKAP PABPC1 PAXIP1 PCBP1 PRPF40A PTBP1 QKI SF3B2 SLU7 SNRPA SRSF3 SRSF7 UBC WDR77 WDR83 YBX1 YBX3
Entrez ID		3191	5094
HPRD ID		04360	03129
Ensembl ID		ENSG00000104824	ENSG00000197111
Uniprot IDs		P14866 Q6NTA2	A0A384N6B9 Q15366
PDB IDs		3R27 3TO8	2AXY 2JZX 2P2R 2PQU 2PY9
Enriched GO Terms of Interacting Partners?
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