HNRNPL and PTBP1

Number of citations of the paper that reports this interaction (PubMedID 26344197)
117

Data Source:
BioGRID (biochemical)
HPRD (in vitro, two hybrid)

		HNRNPL	PTBP1
Description		heterogeneous nuclear ribonucleoprotein L	polypyrimidine tract binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Ribonucleoprotein Granule Pronucleus Perinuclear Region Of Cytoplasm Extracellular Exosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Membrane Extracellular Exosome
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Transcription Regulatory Region DNA Binding Pre-mRNA Intronic Binding MRNA CDS Binding	RNA Binding MRNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing Regulation Of Translation Circadian Rhythm RNA Metabolic Process Cellular Response To Amino Acid Starvation Regulation Of RNA Splicing Positive Regulation Of Translation Negative Regulation Of MRNA Splicing, Via Spliceosome Response To Peptide Positive Regulation Of MRNA Binding	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of Translation RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Negative Regulation Of RNA Splicing Positive Regulation Of Protein Dephosphorylation Regulation Of RNA Splicing Regulation Of Cell Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation Positive Regulation Of Calcineurin-NFAT Signaling Cascade IRES-dependent Viral Translational Initiation
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs		Copper
Diseases
GWAS		Anti-saccade response ( 29064472) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)	Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		16 interacting genes: APEX1 CSE1L CSNK2A1 FGFR3 H3-4 HMG20B HMGA1 HNRNPA2B1 HNRNPK IL7R ITCH NEDD4 PCBP2 PJA1 PTBP1 SUMO4	28 interacting genes: APBB1 APP CALCOCO2 CASP3 FUS H3-4 HIF1A HMGA1 HMGA2 HNRNPAB HNRNPL IL7R LINC00839 MARK4 NONO PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 ZMYM2
Entrez ID		3191	5725
HPRD ID		04360	02823
Ensembl ID		ENSG00000104824	ENSG00000011304
Uniprot IDs		P14866 Q6NTA2	P26599
PDB IDs		3R27 3TO8	1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 2N3O 3ZZY 3ZZZ
Enriched GO Terms of Interacting Partners?
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