CXXC1 and TAX1BP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CXXC1	TAX1BP1
Description		CXXC finger protein 1	Tax1 binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Matrix Nuclear Speck Histone Methyltransferase Complex Set1C/COMPASS Complex	Cytosol Extracellular Exosome
	Molecular Function	Proximal Promoter Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Methyltransferase Activity (H3-K4 Specific) Unmethylated CpG Binding	Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated IRE1-mediated Unfolded Protein Response Positive Regulation Of Transcription, DNA-templated Histone H3-K4 Methylation	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process
Pathways		XBP1(S) activates chaperone genes	Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464)	Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: EP300 MEOX2 NR5A1 PPP1CA SMURF1 TAX1BP1 TBP TP53	40 interacting genes: ARHGAP1 AZI2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN FAM168A FAM189A2 FOXC2 GABARAP GABARAPL1 GABARAPL2 IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RAD54L2 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP3 TRAF6 TRIM14 TSG101 TSHZ3 UBC
Entrez ID		30827	8887
HPRD ID		10852	05618
Ensembl ID		ENSG00000154832	ENSG00000106052
Uniprot IDs		Q9P0U4	B4DSG5 Q86VP1
PDB IDs		3QMB 3QMC 3QMD 3QMG 3QMH 3QMI	2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G
Enriched GO Terms of Interacting Partners?
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