TAX1BP1 and PLEKHN1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TAX1BP1	PLEKHN1
Description		Tax1 binding protein 1	pleckstrin homology domain containing N1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Mitochondrion Cytoskeleton Plasma Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	Phosphatidylserine Binding Protein Binding Phosphatidic Acid Binding Cardiolipin Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process	Response To Hypoxia Positive Regulation Of Apoptotic Process 3'-UTR-mediated MRNA Destabilization
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)	Height ( 31562340) Parkinson's disease ( 26227905)
Interacting Genes		40 interacting genes: ARHGAP1 AZI2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN FAM168A FAM189A2 FOXC2 GABARAP GABARAPL1 GABARAPL2 IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RAD54L2 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP3 TRAF6 TRIM14 TSG101 TSHZ3 UBC	11 interacting genes: CBY2 LPXN LZTS2 PUSL1 REL RFX6 TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27
Entrez ID		8887	84069
HPRD ID		05618	13190
Ensembl ID		ENSG00000106052	ENSG00000187583
Uniprot IDs		B4DSG5 Q86VP1	Q494U1
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G
Enriched GO Terms of Interacting Partners?
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