TAX1BP1 and NMRK1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TAX1BP1	NMRK1
Description		Tax1 binding protein 1	nicotinamide riboside kinase 1
Image
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Cytosol
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	Protein Binding ATP Binding Kinase Activity Metal Ion Binding Ribosylnicotinamide Kinase Activity Ribosylnicotinate Kinase Activity
	Biological Process	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process	NAD Biosynthetic Process Phosphorylation NAD Metabolic Process
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling	Nicotinate metabolism
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)	Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Urinary magnesium-to-creatinine ratio ( 29093028)
Interacting Genes		40 interacting genes: ARHGAP1 AZI2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN FAM168A FAM189A2 FOXC2 GABARAP GABARAPL1 GABARAPL2 IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RAD54L2 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP3 TRAF6 TRIM14 TSG101 TSHZ3 UBC	3 interacting genes: APP GOLGA2 TAX1BP1
Entrez ID		8887	54981
HPRD ID		05618	09868
Ensembl ID		ENSG00000106052	ENSG00000106733
Uniprot IDs		B4DSG5 Q86VP1	B3KUG3 Q5W125 Q9NWW6
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G	2P0E 2QG6 2QL6 2QSY 2QSZ 2QT0 2QT1
Enriched GO Terms of Interacting Partners?
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