TAX1BP1 and TNIP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TAX1BP1	TNIP3
Description		Tax1 binding protein 1	TNFAIP3 interacting protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Cytosol
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process	MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Protein Deubiquitination Toll-like Receptor 4 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling	Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)	Breast cancer ( 23468962) Multiple sclerosis ( 31604244)
Interacting Genes		40 interacting genes: ARHGAP1 AZI2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN FAM168A FAM189A2 FOXC2 GABARAP GABARAPL1 GABARAPL2 IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RAD54L2 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP3 TRAF6 TRIM14 TSG101 TSHZ3 UBC	11 interacting genes: DAZAP2 KRT40 KRTAP10-3 KRTAP10-8 LZTS2 NOTCH2NLA TAX1BP1 TNFAIP3 TNIP1 UBC ZBTB8A
Entrez ID		8887	79931
HPRD ID		05618	16268
Ensembl ID		ENSG00000106052	ENSG00000050730
Uniprot IDs		B4DSG5 Q86VP1	Q96KP6
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G
Enriched GO Terms of Interacting Partners?
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