TAX1BP1 and DSTN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TAX1BP1	DSTN
Description		Tax1 binding protein 1	destrin, actin depolymerizing factor
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Actin Cytoskeleton Cortical Actin Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	Protein Binding Actin Filament Binding
	Biological Process	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process	Actin Polymerization Or Depolymerization Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Actin Filament Severing
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs			Lauryl Dimethylamine-N-Oxide
Diseases
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)	Coronary artery disease ( 29212778) Presence of antiphospholipid antibodies ( 23509613)
Interacting Genes		40 interacting genes: ARHGAP1 AZI2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN FAM168A FAM189A2 FOXC2 GABARAP GABARAPL1 GABARAPL2 IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RAD54L2 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP3 TRAF6 TRIM14 TSG101 TSHZ3 UBC	8 interacting genes: ACTB ACTG1 CFL2 SHBG SMAD9 SSH1 TAX1BP1 TESK2
Entrez ID		8887	11034
HPRD ID		05618	16446
Ensembl ID		ENSG00000106052	ENSG00000125868
Uniprot IDs		B4DSG5 Q86VP1	P60981 V9HWA6
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G
Enriched GO Terms of Interacting Partners?
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