TAX1BP1 and RAB18

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TAX1BP1	RAB18
Description		Tax1 binding protein 1	RAB18, member RAS oncogene family
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Intracellular Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Endomembrane System Secretory Granule Membrane Synapse Endoplasmic Reticulum Tubular Network
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Apoptotic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process	Eye Development Intracellular Protein Transport Small GTPase Mediated Signal Transduction Brain Development Rab Protein Signal Transduction Lipid Droplet Organization Neutrophil Degranulation Import Into Nucleus Endoplasmic Reticulum Tubular Network Organization
Pathways		Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling	Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Warburg micro syndrome
GWAS		Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)	Childhood ear infection ( 27182965 28928442) Diisocyanate-induced asthma ( 25918132) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hip circumference adjusted for BMI ( 28552196)
Interacting Genes		40 interacting genes: ARHGAP1 AZI2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN FAM168A FAM189A2 FOXC2 GABARAP GABARAPL1 GABARAPL2 IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RAD54L2 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP3 TRAF6 TRIM14 TSG101 TSHZ3 UBC	13 interacting genes: APBB1IP CHM DVL3 ERRFI1 FAM107A PDE6D PPP2R1A PPP2R1B PRTFDC1 TAX1BP1 TOM1L1 TREH UCN
Entrez ID		8887	22931
HPRD ID		05618	03731
Ensembl ID		ENSG00000106052	ENSG00000099246
Uniprot IDs		B4DSG5 Q86VP1	A0A087X163 B7Z4P9 B7Z5V3 Q9NP72
PDB IDs		2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G	1X3S
Enriched GO Terms of Interacting Partners?
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