MED4 and CCHCR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MED4	CCHCR1
Description		mediator complex subunit 4	coiled-coil alpha-helical rod protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Mediator Complex Core Mediator Complex	Nucleus Centriole Cytosol
	Molecular Function	Transcription Coregulator Activity Protein Binding Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated	Protein Export From Nucleus Multicellular Organism Development Cell Differentiation
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Feeling nervous ( 29500382) Hematology traits ( 23263863) Inflammatory bowel disease ( 28067908) Microalbuminuria ( 31511532) Multiple myeloma ( 23955597) Nevirapine-induced rash ( 21810746) Night sleep phenotypes ( 27126917) Prostate cancer ( 21743467) Psoriasis ( 30921485) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425) Ulcerative colitis ( 28067908) Urinary albumin-to-creatinine ratio ( 31511532) White blood cell count ( 21738480)
Interacting Genes		33 interacting genes: AMOT AP2M1 ATF7IP C1orf216 CCDC146 CCHCR1 CTDP1 CTNNBL1 FAM13C FOXJ3 FRMD6 FTCD HAUS1 KIFC3 LRRFIP1 MAB21L3 MCRS1 MED30 MED9 NDE1 PCBD2 PUM2 SDCBP SDCBP2 SGF29 SMARCD1 SMARCE1 SSX3 TLE5 TNFAIP8 TXLNA USHBP1 WDTC1	62 interacting genes: ABI2 ALAS1 AMOTL2 ATG5 BLOC1S6 C1orf94 CARD9 CBY2 CCDC102B CCDC136 CDR2 CEP55 CNN1 COG6 EFHC2 FSD2 GLRX3 GOLGA2 GRAP2 HAUS1 HSBP1 HSPB1 IKBKG KRT13 KRT15 KRT31 KRT40 MAD1L1 MED4 MIA2 MID2 MTUS2 NAB2 NDC80 NINL NME7 NUP62 NUTM1 PCM1 PIAS2 POLD2 POLR2C PRKCG RBM17 SAT1 SPAG5 SSX2IP STAR TADA2A TEKT1 TFIP11 TPM3 TRAF1 TRAF2 TRAF4 TRIM27 TSGA10 TXLNA TXLNB USHBP1 WASHC3 ZFYVE19
Entrez ID		29079	54535
HPRD ID		16145	05607
Ensembl ID		ENSG00000136146	ENSG00000204536
Uniprot IDs		A0A024RDY7 Q9NPJ6	A0A1U9X7G6 Q2TB68 Q769H0 Q8TD31
PDB IDs
Enriched GO Terms of Interacting Partners?
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