CCHCR1 and TPM3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		CCHCR1	TPM3
Description		coiled-coil alpha-helical rod protein 1	tropomyosin 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Centriole Cytosol	Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome
	Molecular Function		Molecular_function Protein Binding Actin Filament Binding
	Biological Process	Protein Export From Nucleus Multicellular Organism Development Cell Differentiation	Muscle Contraction Actin Filament Organization Muscle Filament Sliding
Pathways			Striated Muscle Contraction Smooth Muscle Contraction
Drugs			Phenethyl Isothiocyanate
Diseases			Congenital fiber type disproportion (CFTD) Cap myopathy Thyroid cancer Nemaline myopathy
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Feeling nervous ( 29500382) Hematology traits ( 23263863) Inflammatory bowel disease ( 28067908) Microalbuminuria ( 31511532) Multiple myeloma ( 23955597) Nevirapine-induced rash ( 21810746) Night sleep phenotypes ( 27126917) Prostate cancer ( 21743467) Psoriasis ( 30921485) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425) Ulcerative colitis ( 28067908) Urinary albumin-to-creatinine ratio ( 31511532) White blood cell count ( 21738480)	Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		62 interacting genes: ABI2 ALAS1 AMOTL2 ATG5 BLOC1S6 C1orf94 CARD9 CBY2 CCDC102B CCDC136 CDR2 CEP55 CNN1 COG6 EFHC2 FSD2 GLRX3 GOLGA2 GRAP2 HAUS1 HSBP1 HSPB1 IKBKG KRT13 KRT15 KRT31 KRT40 MAD1L1 MED4 MIA2 MID2 MTUS2 NAB2 NDC80 NINL NME7 NUP62 NUTM1 PCM1 PIAS2 POLD2 POLR2C PRKCG RBM17 SAT1 SPAG5 SSX2IP STAR TADA2A TEKT1 TFIP11 TPM3 TRAF1 TRAF2 TRAF4 TRIM27 TSGA10 TXLNA TXLNB USHBP1 WASHC3 ZFYVE19	44 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 DVL2 FAM9C FBXO5 HDDC3 HOOK2 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 NOD2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P
Entrez ID		54535	7170
HPRD ID		05607	01840
Ensembl ID		ENSG00000204536	ENSG00000143549
Uniprot IDs		A0A1U9X7G6 Q2TB68 Q769H0 Q8TD31	A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753
PDB IDs			6OTN
Enriched GO Terms of Interacting Partners?
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