CCHCR1 and HSBP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCHCR1	HSBP1
Description		coiled-coil alpha-helical rod protein 1	heat shock factor binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Centriole Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton
	Molecular Function		Transcription Corepressor Activity Protein Binding Identical Protein Binding
	Biological Process	Protein Export From Nucleus Multicellular Organism Development Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Endodermal Cell Differentiation Cellular Heat Acclimation Regulation Of Cellular Response To Heat
Pathways			HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Feeling nervous ( 29500382) Hematology traits ( 23263863) Inflammatory bowel disease ( 28067908) Microalbuminuria ( 31511532) Multiple myeloma ( 23955597) Nevirapine-induced rash ( 21810746) Night sleep phenotypes ( 27126917) Prostate cancer ( 21743467) Psoriasis ( 30921485) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425) Ulcerative colitis ( 28067908) Urinary albumin-to-creatinine ratio ( 31511532) White blood cell count ( 21738480)	Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		62 interacting genes: ABI2 ALAS1 AMOTL2 ATG5 BLOC1S6 C1orf94 CARD9 CBY2 CCDC102B CCDC136 CDR2 CEP55 CNN1 COG6 EFHC2 FSD2 GLRX3 GOLGA2 GRAP2 HAUS1 HSBP1 HSPB1 IKBKG KRT13 KRT15 KRT31 KRT40 MAD1L1 MED4 MIA2 MID2 MTUS2 NAB2 NDC80 NINL NME7 NUP62 NUTM1 PCM1 PIAS2 POLD2 POLR2C PRKCG RBM17 SAT1 SPAG5 SSX2IP STAR TADA2A TEKT1 TFIP11 TPM3 TRAF1 TRAF2 TRAF4 TRIM27 TSGA10 TXLNA TXLNB USHBP1 WASHC3 ZFYVE19	15 interacting genes: CCHCR1 CD1B HSF1 HSPA1A KIAA1217 KIFC3 KRTAP10-3 KRTAP10-7 LNX1 MPHOSPH6 NOTCH2NLA RPL13 SDCBP SDR42E1 WASHC3
Entrez ID		54535	3281
HPRD ID		05607	05185
Ensembl ID		ENSG00000204536	ENSG00000230989
Uniprot IDs		A0A1U9X7G6 Q2TB68 Q769H0 Q8TD31	O75506
PDB IDs			3CI9
Enriched GO Terms of Interacting Partners?
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