LSM3 and CDKN2D

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		LSM3	CDKN2D
Description		LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated	cyclin dependent kinase inhibitor 2D
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm U6 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Cyclin D2-CDK4 Complex
	Molecular Function	RNA Binding Protein Binding U6 SnRNA 3'-end Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle DNA Synthesis Involved In DNA Repair Cell Cycle Arrest Sensory Perception Of Sound Negative Regulation Of Cell Proliferation Response To UV Negative Regulation Of Cell Growth Response To Retinoic Acid Response To Vitamin D Negative Regulation Of Phosphorylation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Autophagic Cell Death Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway	Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Cyclin D associated events in G1
Drugs
Diseases
GWAS		Chronotype ( 30696823) Height ( 31562340) Offspring birth weight ( 31043758)
Interacting Genes		40 interacting genes: CCND3 CDKN2D CEP95 CLNS1A CNOT7 DLX4 EEF1A1 EIF4EBP2 EXOSC1 EXOSC5 GDF9 GSTA1 HSPB1 KEAP1 KLF3 LSM1 LSM10 LSM2 LSM5 LSM6 LSM7 LSM8 PIAS1 QKI SF3B2 SH3GLB2 SMN1 SNRPD1 SNRPD3 SNRPE SNRPG TCL1A TFIP11 THOC5 UTP14A WDR77 WDR83 XPC XRN2 YBX1	22 interacting genes: APP BRCA1 BTG1 C1orf94 CDK4 CDK6 CTBP1 DMRTB1 FHL3 HSD17B14 IKZF3 INCA1 LSM3 NMI NR4A1 NR4A2 QKI SH3GLB1 SH3GLB2 TBC1D17 TEX11 TSG101
Entrez ID		27258	1032
HPRD ID		06283	02957
Ensembl ID		ENSG00000170860	ENSG00000129355
Uniprot IDs		P62310	A0A024R796 P55273
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	1BD8 1BI8
Enriched GO Terms of Interacting Partners?
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