LSM3 and LSM5

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (biochemical, affinity chromatography technology, two hybrid)
HPRD (in vitro)

		LSM3	LSM5
Description		LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated	LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm U6 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex	Nucleus Nucleoplasm U6 SnRNP Cytoplasm Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex
	Molecular Function	RNA Binding Protein Binding U6 SnRNA 3'-end Binding	Protein Binding Protein Heterodimerization Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	MRNA Splicing, Via Spliceosome MRNA Processing MRNA Catabolic Process Response To Bacterium Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Chronotype ( 30696823) Height ( 31562340) Offspring birth weight ( 31043758)	Body mass index ( 26426971) Extremely high intelligence ( 29520040) Morning person ( 30696823) Palmitic acid (16:0) levels ( 23362303) Smooth-surface caries ( 24556642)
Interacting Genes		40 interacting genes: CCND3 CDKN2D CEP95 CLNS1A CNOT7 DLX4 EEF1A1 EIF4EBP2 EXOSC1 EXOSC5 GDF9 GSTA1 HSPB1 KEAP1 KLF3 LSM1 LSM10 LSM2 LSM5 LSM6 LSM7 LSM8 PIAS1 QKI SF3B2 SH3GLB2 SMN1 SNRPD1 SNRPD3 SNRPE SNRPG TCL1A TFIP11 THOC5 UTP14A WDR77 WDR83 XPC XRN2 YBX1	11 interacting genes: EXOSC5 HNRNPD LSM1 LSM2 LSM3 LSM6 LSM7 LSM8 SMN1 SNRPE SNRPF
Entrez ID		27258	23658
HPRD ID		06283	06285
Ensembl ID		ENSG00000170860	ENSG00000106355
Uniprot IDs		P62310	A0A090N8Y5 Q9Y4Y9
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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