CDKN2D and INCA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CDKN2D	INCA1
Description		cyclin dependent kinase inhibitor 2D	inhibitor of CDK, cyclin A1 interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cyclin D2-CDK4 Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Cyclin Binding Protein-containing Complex Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle DNA Synthesis Involved In DNA Repair Cell Cycle Arrest Sensory Perception Of Sound Negative Regulation Of Cell Proliferation Response To UV Negative Regulation Of Cell Growth Response To Retinoic Acid Response To Vitamin D Negative Regulation Of Phosphorylation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Autophagic Cell Death Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Negative Regulation Of Cell Proliferation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Cyclin D associated events in G1
Drugs
Diseases
GWAS			Intraocular pressure ( 29235454) Obesity-related traits ( 23251661)
Interacting Genes		22 interacting genes: APP BRCA1 BTG1 C1orf94 CDK4 CDK6 CTBP1 DMRTB1 FHL3 HSD17B14 IKZF3 INCA1 LSM3 NMI NR4A1 NR4A2 QKI SH3GLB1 SH3GLB2 TBC1D17 TEX11 TSG101	39 interacting genes: ARMC7 CABP5 CCNA1 CDC23 CDK2 CDKN2D CHCHD2 COL8A1 CTNNBIP1 DAZAP2 DMRT3 DPH7 EPHB6 FHL2 FMR1 GRB2 HAUS1 NEK6 OSGIN1 PATE1 PTGER3 RAB5C RAMAC RBPMS RNF26 SAP18 SCNM1 SEC14L4 SPG21 SPOUT1 STAMBPL1 STK16 TRIM26 TRIP6 UBE2D4 UBXN2B VPS28 ZMYND19 ZNF205-AS1
Entrez ID		1032	388324
HPRD ID		02957	17150
Ensembl ID		ENSG00000129355	ENSG00000196388
Uniprot IDs		A0A024R796 P55273	Q0VD86
PDB IDs		1BD8 1BI8
Enriched GO Terms of Interacting Partners?
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