GEM and COG8

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GEM	COG8
Description		GTP binding protein overexpressed in skeletal muscle	component of oligomeric golgi complex 8
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle	Golgi Membrane Golgi Apparatus Membrane Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	Magnesium Ion Binding GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Chromosome Organization Metaphase Plate Congression Negative Regulation Of High Voltage-gated Calcium Channel Activity	ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Transport
Pathways			COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Carotid plaque burden ( 28282560) Coronary artery disease ( 29212778) Pulse pressure ( 30578418)	Body mass index ( 26426971) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		41 interacting genes: A2M AHCYL1 APOH BLZF1 BMP1 CALM1 CCDC102B CLDN15 CLEC4G COG8 CTSL DEUP1 GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NLA PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB	5 interacting genes: CYB5B GEM HGS MTNR1B MYEF2
Entrez ID		2669	84342
HPRD ID		11553	07374
Ensembl ID		ENSG00000164949	ENSG00000213380
Uniprot IDs		A0A024R9F5 P55040	A0A024R6Z6 Q96MW5
PDB IDs		2CJW 2G3Y 2HT6
Enriched GO Terms of Interacting Partners?
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