GEM and CLDN15

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GEM	CLDN15
Description		GTP binding protein overexpressed in skeletal muscle	claudin 15
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle	Bicellular Tight Junction Integral Component Of Membrane Lateral Plasma Membrane
	Molecular Function	Magnesium Ion Binding GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding	Structural Molecule Activity Identical Protein Binding
	Biological Process	Mitotic Cell Cycle Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Chromosome Organization Metaphase Plate Congression Negative Regulation Of High Voltage-gated Calcium Channel Activity	Ion Transport Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Pathways			Tight junction interactions
Drugs
Diseases
GWAS		Carotid plaque burden ( 28282560) Coronary artery disease ( 29212778) Pulse pressure ( 30578418)
Interacting Genes		41 interacting genes: A2M AHCYL1 APOH BLZF1 BMP1 CALM1 CCDC102B CLDN15 CLEC4G COG8 CTSL DEUP1 GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NLA PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB	1 interacting genes: GEM
Entrez ID		2669	24146
HPRD ID		11553	13065
Ensembl ID		ENSG00000164949	ENSG00000106404
Uniprot IDs		A0A024R9F5 P55040	P56746
PDB IDs		2CJW 2G3Y 2HT6
Enriched GO Terms of Interacting Partners?
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