GEM and BMP1

Number of citations of the paper that reports this interaction (PubMedID 18624398)
14

Data Source:
BioGRID (two hybrid)

		GEM	BMP1
Description		GTP binding protein overexpressed in skeletal muscle	bone morphogenetic protein 1
Image
GO Annotations	Cellular Component	Cell Nucleus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle	Extracellular Region Extracellular Space Golgi Apparatus Vesicle
	Molecular Function	Magnesium Ion Binding GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding	Metalloendopeptidase Activity Cytokine Activity Calcium Ion Binding Protein Binding Growth Factor Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Identical Protein Binding
	Biological Process	Mitotic Cell Cycle Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Chromosome Organization Metaphase Plate Congression Negative Regulation Of High Voltage-gated Calcium Channel Activity	Skeletal System Development Cartilage Condensation Ossification Proteolysis Signal Transduction Multicellular Organism Development Extracellular Matrix Disassembly Cell Differentiation High-density Lipoprotein Particle Assembly Positive Regulation Of Cartilage Development
Pathways			Degradation of the extracellular matrix Degradation of the extracellular matrix Collagen biosynthesis and modifying enzymes Anchoring fibril formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Carotid plaque burden ( 28282560) Coronary artery disease ( 29212778) Pulse pressure ( 30578418)	Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		41 interacting genes: A2M AHCYL1 APOH BLZF1 BMP1 CALM1 CCDC102B CLDN15 CLEC4G COG8 CTSL DEUP1 GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NLA PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB	14 interacting genes: ADRA1A CHRD COL1A1 COL5A1 COL5A2 COL7A1 GEM HSPG2 LAMA3 LAMB3 LAMC2 TP53 TWSG1 YLPM1
Entrez ID		2669	649
HPRD ID		11553	00209
Ensembl ID		ENSG00000164949	ENSG00000168487
Uniprot IDs		A0A024R9F5 P55040	P13497
PDB IDs		2CJW 2G3Y 2HT6	3EDG 3EDH 6BSL 6BSM 6BTN 6BTO 6BTP 6BTQ
Enriched GO Terms of Interacting Partners?
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