SPG21 and TFG

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SPG21	TFG
Description		SPG21 abhydrolase domain containing, maspardin	trafficking from ER to golgi regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Endosome Membrane Trans-Golgi Network Transport Vesicle Intracellular Membrane-bounded Organelle	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding CD4 Receptor Binding	Protein Binding Identical Protein Binding
	Biological Process	Antigen Receptor-mediated Signaling Pathway	ER To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating
Pathways			COPII-mediated vesicle transport
Drugs
Diseases		Hereditary spastic paraplegia (SPG)	Non-small cell lung cancer Thyroid cancer
GWAS
Interacting Genes		37 interacting genes: AGTRAP AKIRIN2 ARL6IP1 CCDC102B CCDC33 CD4 CMTM5 CRYAA CTPS2 CUTC DTX2 DTX3L EFHC2 FAM114A1 GGA2 GSK3A IKZF3 INCA1 KRT15 LMNA MID2 MTMR9 PRPS1 RABAC1 REEP6 RTN4 S100B SPRED2 TCF12 TCF4 TFG TRAF1 TRAF2 TRIM23 TRIM54 TRIM9 ZNF263	32 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL CEP126 CEP55 CRMP1 CSTF2 ERG28 EWSR1 GBP2 GPRASP1 GRB2 HGS HNRNPF MAGED1 MAPK1IP1L MED21 MYOT PEF1 PIN1 PLSCR1 PTPN6 RBPMS RIPPLY2 SEC24A SPG21 STAT5B TOMM70 TRIM25 TSSK2 VPS37C
Entrez ID		51324	10342
HPRD ID		10492	03932
Ensembl ID		ENSG00000090487	ENSG00000114354
Uniprot IDs		A0A024R5Y1 Q9NZD8	Q05BK6 Q92734
PDB IDs
Enriched GO Terms of Interacting Partners?
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