FHL3 and ZNRD1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FHL3	ZNRD1
Description		four and a half LIM domains 3	zinc ribbon domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Focal Adhesion Z Disc	Nucleoplasm RNA Polymerase I Complex
	Molecular Function	Transcription Coregulator Activity Actin Binding Protein Binding Metal Ion Binding	Nucleic Acid Binding DNA-directed 5'-3' RNA Polymerase Activity Zinc Ion Binding
	Biological Process	Muscle Organ Development Actin Cytoskeleton Organization Regulation Of Nucleic Acid-templated Transcription	Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription MRNA Cleavage Positive Regulation Of Gene Expression, Epigenetic
Pathways			NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Pulse pressure ( 30578418)	AIDS progression ( 19115949) Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) HIV-1 control ( 20041166) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		125 interacting genes: A1CF ACTB ADAM15 ADAMTSL4 AIMP2 AMBP ANKHD1 C9orf116 CCDC198 CCND3 CDC25B CDC42EP1 CDKN1A CDKN2D CHEK2 CLCN2 CNNM3 CNOT7 CORO1A CSF1 CTBP2 DCDC2B E2F8 EFCAB12 EIF4EBP2 EPHA10 EPM2AIP1 EXOSC1 EXOSC5 FAM126A FAM71C FAM90A1 FBXL18 FHL2 FOS FOSL2 FOXN4 GATA1 GATA2 GCM2 HIPK1 HYAL2 IHO1 IKZF3 ITGA7 KIRREL2 KLF3 KLF8 KPRP KRTAP12-1 KRTAP12-2 KTI12 LASP1 LATS2 LMO2 LNX1 LNX2 MAPK1 MED15 MORF4L1 MPZL1 MRM3 MRPL27 MTA1 MTUS2 MYBPC1 MYBPHL MZF1 NFKBIB NPRL3 P4HA2 PAK5 PATL1 PHC2 PHF21A PIAS1 PLEKHF2 PLEKHG4B PPIG PTPN6 QKI QRICH1 RAB40B RAD21 RBM42 RFX3 RFX6 RHEBL1 RYBP SAP30BP SAXO1 SH3GLB2 SLAIN1 SLC25A46 SLC44A3 SMAD2 SMAD3 SMAD4 SNRPG SPATA8 SREBF2 SRF SRGN SUPT5H THEG TLE5 TMEM14B TMX3 TOPBP1 TRAF3IP2 TRIM27 TRIP6 TRO TTLL10 TYK2 TYMSOS UBE2I UBE2Q1 VWC2L WNK1 YPEL3 ZFP36 ZNF417 ZNF512B ZNRD1	17 interacting genes: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP MAPK8IP2 NONO SACS SERPINA3 TNS2 UBE2I ZNF593
Entrez ID		2275	30834
HPRD ID		09101	09601
Ensembl ID		ENSG00000183386	ENSG00000066379
Uniprot IDs		Q13643 Q96C98	Q2L6J2 Q9P1U0
PDB IDs		1WYH 2CUQ 2EHE
Enriched GO Terms of Interacting Partners?
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