FHL3 and AMBP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FHL3	AMBP
Description		four and a half LIM domains 3	alpha-1-microglobulin/bikunin precursor
Image
GO Annotations	Cellular Component	Stress Fiber Nucleus Focal Adhesion Z Disc	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Transcription Coregulator Activity Actin Binding Protein Binding Metal Ion Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding Calcium Channel Inhibitor Activity IgA Binding Heme Binding Protein Homodimerization Activity Calcium Oxalate Binding
	Biological Process	Muscle Organ Development Actin Cytoskeleton Organization Regulation Of Nucleic Acid-templated Transcription	Receptor-mediated Endocytosis Cell Adhesion Female Pregnancy Negative Regulation Of Endopeptidase Activity Viral Process Protein-chromophore Linkage Protein Catabolic Process Heme Catabolic Process Negative Regulation Of JNK Cascade Negative Regulation Of Immune Response
Pathways			Scavenging of heme from plasma
Drugs			Human Serum Albumin
Diseases
GWAS		Coronary artery disease ( 29212778) Pulse pressure ( 30578418)	Blood protein levels ( 29875488)
Interacting Genes		125 interacting genes: A1CF ACTB ADAM15 ADAMTSL4 AIMP2 AMBP ANKHD1 C9orf116 CCDC198 CCND3 CDC25B CDC42EP1 CDKN1A CDKN2D CHEK2 CLCN2 CNNM3 CNOT7 CORO1A CSF1 CTBP2 DCDC2B E2F8 EFCAB12 EIF4EBP2 EPHA10 EPM2AIP1 EXOSC1 EXOSC5 FAM126A FAM71C FAM90A1 FBXL18 FHL2 FOS FOSL2 FOXN4 GATA1 GATA2 GCM2 HIPK1 HYAL2 IHO1 IKZF3 ITGA7 KIRREL2 KLF3 KLF8 KPRP KRTAP12-1 KRTAP12-2 KTI12 LASP1 LATS2 LMO2 LNX1 LNX2 MAPK1 MED15 MORF4L1 MPZL1 MRM3 MRPL27 MTA1 MTUS2 MYBPC1 MYBPHL MZF1 NFKBIB NPRL3 P4HA2 PAK5 PATL1 PHC2 PHF21A PIAS1 PLEKHF2 PLEKHG4B PPIG PTPN6 QKI QRICH1 RAB40B RAD21 RBM42 RFX3 RFX6 RHEBL1 RYBP SAP30BP SAXO1 SH3GLB2 SLAIN1 SLC25A46 SLC44A3 SMAD2 SMAD3 SMAD4 SNRPG SPATA8 SREBF2 SRF SRGN SUPT5H THEG TLE5 TMEM14B TMX3 TOPBP1 TRAF3IP2 TRIM27 TRIP6 TRO TTLL10 TYK2 TYMSOS UBE2I UBE2Q1 VWC2L WNK1 YPEL3 ZFP36 ZNF417 ZNF512B ZNRD1	13 interacting genes: A2M ALB COX8A DAAM1 ENO1 EXOSC2 F2 FHL3 FN1 GRB2 PIK3CA PIK3R3 STAT3
Entrez ID		2275	259
HPRD ID		09101	01467
Ensembl ID		ENSG00000183386	ENSG00000106927
Uniprot IDs		Q13643 Q96C98	P02760
PDB IDs		1WYH 2CUQ 2EHE	1BIK 3QKG 4ES7 4U30 6EJ7 6EJ8 6EJ9 6EJA 6EJB 6EJC 6EJD
Enriched GO Terms of Interacting Partners?
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