ZNRD1 and GPR20

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ZNRD1	GPR20
Description		zinc ribbon domain containing 1	G protein-coupled receptor 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase I Complex	Cell Cytosol Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Nucleic Acid Binding DNA-directed 5'-3' RNA Polymerase Activity Zinc Ion Binding	G Protein-coupled Receptor Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription MRNA Cleavage Positive Regulation Of Gene Expression, Epigenetic	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		AIDS progression ( 19115949) Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) HIV-1 control ( 20041166) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730)	Bipolar disorder ( 21926972) Birth weight ( 31043758) Blood pressure traits (multi-trait analysis) ( 28498854) Diastolic blood pressure ( 27841878 27618447 28498854) Discordance in emotional problems in monozygotic twins ( 27043157) Height ( 31562340) Response to fenofibrate (total cholesterol levels) ( 27002377) Systolic blood pressure ( 27841878 27618447 28498854 31217584)
Interacting Genes		17 interacting genes: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP MAPK8IP2 NONO SACS SERPINA3 TNS2 UBE2I ZNF593	3 interacting genes: JAM2 RPL31 ZNRD1
Entrez ID		30834	2843
HPRD ID		09601	03550
Ensembl ID		ENSG00000066379	ENSG00000204882
Uniprot IDs		Q2L6J2 Q9P1U0	Q59GP3 Q99678
PDB IDs
Enriched GO Terms of Interacting Partners?
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