RNF6 and MAGED1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		RNF6	MAGED1
Description		ring finger protein 6	MAGE family member D1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm PML Body Axon Nuclear Membrane Intracellular Membrane-bounded Organelle	Chromatin Nucleus Cytoplasm Plasma Membrane Protein-containing Complex
	Molecular Function	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Androgen Receptor Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Axon Extension Protein K27-linked Ubiquitination Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Protein K48-linked Ubiquitination Protein K6-linked Ubiquitination	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Positive Regulation Of MAP Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	NRAGE signals death through JNK Caspase activation via Dependence Receptors in the absence of ligand
Drugs
Diseases
GWAS		Sporadic pituitary adenoma ( 26029870) Type 2 diabetes ( 24509480 30297969 30718926 28869590) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		36 interacting genes: AHCYL1 AR CBY2 CCDC33 CCDC57 CEP70 GOLGA2 HOOK2 IKZF1 IKZF3 KIAA0753 KRT15 KRT40 LDOC1 MAGED1 MDFI MEOX2 MID2 MIPOL1 MTUS2 PNMA2 REL RINT1 RPGRIP1 SSX2IP STX11 TADA2A TCF4 TFIP11 TNS2 TRIM23 TRIM27 TRIM37 TSGA10 UBE2D1 UBE2H	62 interacting genes: AKAP9 ARNT2 BAG3 BARD1 BHLHE40 BIRC8 BRCA2 C1orf94 CA8 CCDC33 DAB1 DAZAP2 DLX4 DLX5 EIF3J EIF4E2 EP300 GPR135 GRAP2 HGS HIVEP1 HNRNPLL KPNA2 KRTAP19-5 MAPK3 MDFI MEOX2 MPC1 MSX2 NGFR NOTCH1 NPAS4 NUMBL PITX1 PJA1 PJA2 PLK1 PRKAB2 PSMF1 RBFOX1 RBFOX2 RBM23 RBPMS RFX1 RHOXF2 RNF6 RNF8 ROR2 SIM2 SIRT7 SMAP2 SNRPC TFG TRAF4 TRIM28 TTC23 TTC32 TUBA4A UNC5A XIAP ZNF488 ZNF688
Entrez ID		6049	9500
HPRD ID		05027	02202
Ensembl ID		ENSG00000127870	ENSG00000179222
Uniprot IDs		A0A024RDP2 A0A0S2Z4G9 Q9Y252	Q9Y5V3
PDB IDs
Enriched GO Terms of Interacting Partners?
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