RAB3IP and PPL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RAB3IP	PPL
Description		RAB3A interacting protein	periplakin
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GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Lamellipodium	Cornified Envelope Nucleus Cytoplasm Mitochondrion Cytosol Cytoskeleton Intermediate Filament Membrane Desmosome Extracellular Exosome
	Molecular Function	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Cadherin Binding
	Biological Process	Protein Targeting To Membrane Ciliary Basal Body-plasma Membrane Docking	Response To Mechanical Stimulus Wound Healing Intermediate Filament Cytoskeleton Organization Cornification
Pathways		Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs	Formation of the cornified envelope Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)	Cancer ( 29299148) Diastolic blood pressure ( 28135244 27841878) Height ( 28552196) Lung cancer (asbestos exposure interaction) ( 22637743) Metabolite levels (HVA/MHPG ratio) ( 23319000) Mitochondrial DNA copy number (white blood cells) ( 30704525) Systolic blood pressure ( 27841878)
Interacting Genes		21 interacting genes: BANP CHCHD3 FAM124A KRT40 MVP NAA10 PLOD3 PPL RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TRAPPC6A TXNDC5 ZNF410	24 interacting genes: AHCYL1 AKT1 ALAS1 CASP6 CEP57L1 COL17A1 EVPL ITSN1 KAZN KRT8 LARP1 OPRM1 PPHLN1 PTEN RAB3IP RALBP1 SKIL TRAF2 TRIM27 TSC22D4 UBC USP7 VIM ZSCAN1
Entrez ID		117177	5493
HPRD ID		10565	04187
Ensembl ID		ENSG00000127328	ENSG00000118898
Uniprot IDs		Q96QF0	O60437
PDB IDs		4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P	4Q28
Enriched GO Terms of Interacting Partners?
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