PTPN9 and AGTRAP

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		PTPN9	AGTRAP
Description		protein tyrosine phosphatase non-receptor type 9	angiotensin II receptor associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Neuron Projection Terminus	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	Angiotensin Type II Receptor Activity Protein Binding
	Biological Process	Protein Dephosphorylation Negative Regulation Of Neuron Projection Development Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus Positive Regulation Of Protein Localization To Plasma Membrane	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway
Pathways		Interleukin-37 signaling	Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Height ( 25429064 31562340 20189936) Type 2 diabetes ( 30297969)	Systolic blood pressure ( 19430483)
Interacting Genes		10 interacting genes: AGTRAP CMTM5 CREB3 GHR LMNA MAL2 NSF REEP6 RTN3 STX6	79 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 ARHGAP1 BPIFA2 CAPNS1 CD160 CIAO2A COQ8A CPLX1 CRCT1 DDA1 DDX55 DGCR6 DIABLO ECPAS FAM114A1 FAM160A2 FARS2 FASTKD3 FATE1 FGA GABARAPL2 GAD1 GAD2 GDNF GTF3C1 H4C7 HARS2 HMGB1 HSCB HSPA4 ISCU LMNA LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH MYG1 NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PIMREG PITPNC1 PNPO PTPN9 RACK1 RMDN2 S100B SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TMEM14B TPD52L3 TUBA1B TXN2 UBE2I ZFYVE21 ZNF391
Entrez ID		5780	57085
HPRD ID		02864	16379
Ensembl ID		ENSG00000169410	ENSG00000177674
Uniprot IDs		P43378 Q6IQ43	Q6RW13
PDB IDs		2PA5 4GE2 4GE5 4GE6 4ICZ
Enriched GO Terms of Interacting Partners?
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