PTPN9 and STX6

Number of citations of the paper that reports this interaction (PubMedID 15322554)
37

Data Source:
HPRD (in vitro)

		PTPN9	STX6
Description		protein tyrosine phosphatase non-receptor type 9	syntaxin 6
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Neuron Projection Terminus	Golgi Membrane Nucleoplasm Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Clathrin-coated Vesicle Integral Component Of Synaptic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Protein Dephosphorylation Negative Regulation Of Neuron Projection Development Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus Positive Regulation Of Protein Localization To Plasma Membrane	Intracellular Protein Transport Vesicle Fusion Endosome Organization Synaptic Vesicle To Endosome Fusion Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking Golgi Ribbon Formation Regulation Of Cellular Protein Localization
Pathways		Interleukin-37 signaling	Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Height ( 25429064 31562340 20189936) Type 2 diabetes ( 30297969)	Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 30089514 21685912)
Interacting Genes		10 interacting genes: AGTRAP CMTM5 CREB3 GHR LMNA MAL2 NSF REEP6 RTN3 STX6	15 interacting genes: DNAJC5 EEA1 GOPC LMNA MARCHF2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX7 VAMP4 VPS11 VPS18
Entrez ID		5780	10228
HPRD ID		02864	07231
Ensembl ID		ENSG00000169410	ENSG00000135823
Uniprot IDs		P43378 Q6IQ43	O43752
PDB IDs		2PA5 4GE2 4GE5 4GE6 4ICZ	2NPS 4J2C
Enriched GO Terms of Interacting Partners?
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