TRAF3IP2 and FHL3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRAF3IP2	FHL3
Description		TRAF3 interacting protein 2	four and a half LIM domains 3
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Stress Fiber Nucleus Focal Adhesion Z Disc
	Molecular Function	Signaling Receptor Binding Protein Binding	Transcription Coregulator Activity Actin Binding Protein Binding Metal Ion Binding
	Biological Process	B Cell Apoptotic Process Positive Regulation Of Defense Response To Virus By Host Humoral Immune Response Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immunoglobulin Secretion	Muscle Organ Development Actin Cytoskeleton Organization Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Inflammatory bowel disease ( 28067908 23128233) Inflammatory skin disease ( 25574825) Intraocular pressure ( 29617998) Psoriasis ( 25903422 20953188 20953190 25574825 23143594) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624 20953186) Smoking status (ever vs never smokers) ( 30643258) Ulcerative colitis ( 28067908)	Coronary artery disease ( 29212778) Pulse pressure ( 30578418)
Interacting Genes		21 interacting genes: CD40 CHUK FHL3 GOLGA2 HSD17B10 IKBKB IKBKG MAP3K7 MDFI MRPL28 RIMBP3 STK16 TBK1 TRAF1 TRAF2 TRAF3 TRAF5 TRAF6 TRIP6 UBC UBE2V1	125 interacting genes: A1CF ACTB ADAM15 ADAMTSL4 AIMP2 AMBP ANKHD1 C9orf116 CCDC198 CCND3 CDC25B CDC42EP1 CDKN1A CDKN2D CHEK2 CLCN2 CNNM3 CNOT7 CORO1A CSF1 CTBP2 DCDC2B E2F8 EFCAB12 EIF4EBP2 EPHA10 EPM2AIP1 EXOSC1 EXOSC5 FAM126A FAM71C FAM90A1 FBXL18 FHL2 FOS FOSL2 FOXN4 GATA1 GATA2 GCM2 HIPK1 HYAL2 IHO1 IKZF3 ITGA7 KIRREL2 KLF3 KLF8 KPRP KRTAP12-1 KRTAP12-2 KTI12 LASP1 LATS2 LMO2 LNX1 LNX2 MAPK1 MED15 MORF4L1 MPZL1 MRM3 MRPL27 MTA1 MTUS2 MYBPC1 MYBPHL MZF1 NFKBIB NPRL3 P4HA2 PAK5 PATL1 PHC2 PHF21A PIAS1 PLEKHF2 PLEKHG4B PPIG PTPN6 QKI QRICH1 RAB40B RAD21 RBM42 RFX3 RFX6 RHEBL1 RYBP SAP30BP SAXO1 SH3GLB2 SLAIN1 SLC25A46 SLC44A3 SMAD2 SMAD3 SMAD4 SNRPG SPATA8 SREBF2 SRF SRGN SUPT5H THEG TLE5 TMEM14B TMX3 TOPBP1 TRAF3IP2 TRIM27 TRIP6 TRO TTLL10 TYK2 TYMSOS UBE2I UBE2Q1 VWC2L WNK1 YPEL3 ZFP36 ZNF417 ZNF512B ZNRD1
Entrez ID		10758	2275
HPRD ID		06129	09101
Ensembl ID		ENSG00000056972	ENSG00000183386
Uniprot IDs		O43734	Q13643 Q96C98
PDB IDs			1WYH 2CUQ 2EHE
Enriched GO Terms of Interacting Partners?
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