TRAF3IP2 and HSD17B10

Number of citations of the paper that reports this interaction (PubMedID 22496890)
5

Data Source:
BioGRID (two hybrid)

		TRAF3IP2	HSD17B10
Description		TRAF3 interacting protein 2	hydroxysteroid 17-beta dehydrogenase 10
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Cytoplasm Mitochondrion Mitochondrial Matrix Plasma Membrane Mitochondrial Ribonuclease P Complex
	Molecular Function	Signaling Receptor Binding Protein Binding	TRNA Binding RNA Binding 3-hydroxyacyl-CoA Dehydrogenase Activity Protein Binding Cholate 7-alpha-dehydrogenase Activity Testosterone Dehydrogenase [NAD(P)] Activity Dihydrotestosterone 17-beta-dehydrogenase Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity
	Biological Process	B Cell Apoptotic Process Positive Regulation Of Defense Response To Virus By Host Humoral Immune Response Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immunoglobulin Secretion	Lipid Metabolic Process Mitochondrion Organization Branched-chain Amino Acid Catabolic Process Protein Homotetramerization Oxidation-reduction Process Mitochondrial TRNA Methylation Mitochondrial TRNA Processing Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing
Pathways			tRNA processing in the mitochondrion tRNA modification in the mitochondrion Branched-chain amino acid catabolism rRNA processing in the mitochondrion
Drugs			NADH 1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct
Diseases			2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency; HSD10 deficiency Non-syndromic X-linked mental retardation Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS		Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Inflammatory bowel disease ( 28067908 23128233) Inflammatory skin disease ( 25574825) Intraocular pressure ( 29617998) Psoriasis ( 25903422 20953188 20953190 25574825 23143594) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624 20953186) Smoking status (ever vs never smokers) ( 30643258) Ulcerative colitis ( 28067908)	Bipolar disorder ( 31043756) Body mass index ( 28892062)
Interacting Genes		21 interacting genes: CD40 CHUK FHL3 GOLGA2 HSD17B10 IKBKB IKBKG MAP3K7 MDFI MRPL28 RIMBP3 STK16 TBK1 TRAF1 TRAF2 TRAF3 TRAF5 TRAF6 TRIP6 UBC UBE2V1	31 interacting genes: ALDH3B1 ALDOA APP ATP5F1A CHD3 CPS1 CS ETFDH FAF1 GLUD1 GLUL HADHA HADHB HMGCL HMGCS2 HTRA2 MDH1 OGDH PDHA1 PDHB PDHX PINK1 PRKN PYGL TOMM20 TOMM22 TOMM40 TRAF3IP2 TRAF5 TRAF6 UBE2D1
Entrez ID		10758	3028
HPRD ID		06129	02223
Ensembl ID		ENSG00000056972	ENSG00000072506
Uniprot IDs		O43734	A0A0S2Z410 Q99714
PDB IDs			1F67 1SO8 1U7T 2O23
Enriched GO Terms of Interacting Partners?
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