GLRX3 and GMCL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		GLRX3	GMCL1
Description		glutaredoxin 3	germ cell-less 1, spermatogenesis associated
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytosol Cell Cortex Z Disc Dendrite	Nucleus Nuclear Matrix
	Molecular Function	RNA Binding Protein Kinase C Binding Protein Binding Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Cellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy Electron Transport Chain [2Fe-2S] Cluster Assembly Cell Redox Homeostasis Protein Maturation By Iron-sulfur Cluster Transfer	Multicellular Organism Development Spermatogenesis Cell Differentiation
Pathways		Iron uptake and transport
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)	Atrial fibrillation ( 28416818 30061737 29892015) Colorectal or endometrial cancer ( 26621817) Whole brain grey matter density ( 31530798)
Interacting Genes		69 interacting genes: ADAMTSL4 ALKBH3 BCL6 BOLA1 CA9 CBLB CCHCR1 CGGBP1 CIAPIN1 EFEMP2 FAM118A FRA10AC1 GATA1 GMCL1 GRN HEXD IHO1 IKZF1 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE2D LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI MOXD1 NADK NOTCH2NLA OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ PRKD2 RGS20 SOX7 STAU1 TCF4 TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF148 ZNF23 ZNF426 ZNF512B ZNF544	63 interacting genes: APLF APOL6 AXIN1 BYSL C5orf60 CCDC25 CFAP410 CHIC2 CIB3 CLK2 CUL3 ELOA EMD FKBP1B FOSL2 FOXR1 FRMD6 GAGE1 GAGE12B GAGE12I GAGE2E GAGE5 GLRX3 GMCL2 GOLGA2 GRAMD1A HYKK IL17F KAT5 KIFC3 KPNA2 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR NEBL NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PTPN7 QRICH1 RAD54B SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 TMPO TRIM13 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 ZNF250
Entrez ID		10539	64395
HPRD ID		10153	13587
Ensembl ID		ENSG00000108010	ENSG00000087338
Uniprot IDs		A0A140VJK1 O76003	Q53SE7 Q96IK5
PDB IDs		2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?
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