GMCL1 and GRAMD1A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GMCL1	GRAMD1A
Description		germ cell-less 1, spermatogenesis associated	GRAM domain containing 1A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Matrix	Autophagosome Cytosol Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Endoplasmic Reticulum Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle Organelle Membrane Contact Site
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Cholesterol Binding Intermembrane Cholesterol Transfer Activity
	Biological Process	Multicellular Organism Development Spermatogenesis Cell Differentiation	Autophagy Sterol Transport Cellular Response To Cholesterol
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 30061737 29892015) Colorectal or endometrial cancer ( 26621817) Whole brain grey matter density ( 31530798)	Cognitive decline (age-related) ( 28078323) Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		63 interacting genes: APLF APOL6 AXIN1 BYSL C5orf60 CCDC25 CFAP410 CHIC2 CIB3 CLK2 CUL3 ELOA EMD FKBP1B FOSL2 FOXR1 FRMD6 GAGE1 GAGE12B GAGE12I GAGE2E GAGE5 GLRX3 GMCL2 GOLGA2 GRAMD1A HYKK IL17F KAT5 KIFC3 KPNA2 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR NEBL NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PTPN7 QRICH1 RAD54B SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 TMPO TRIM13 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 ZNF250	2 interacting genes: GMCL1 TLR7
Entrez ID		64395	57655
HPRD ID		13587	11153
Ensembl ID		ENSG00000087338	ENSG00000089351
Uniprot IDs		Q53SE7 Q96IK5	B3KQF7 B3KUH3 M0QZ12 Q96CP6
PDB IDs
Enriched GO Terms of Interacting Partners?
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