GLRX3 and TMEM25

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GLRX3	TMEM25
Description		glutaredoxin 3	transmembrane protein 25
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytosol Cell Cortex Z Disc Dendrite	Extracellular Region Lysosome Late Endosome Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Protein Kinase C Binding Protein Binding Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding	Protein Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Cellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy Electron Transport Chain [2Fe-2S] Cluster Assembly Cell Redox Homeostasis Protein Maturation By Iron-sulfur Cluster Transfer	Regulation Of Protein Stability Negative Regulation Of Excitatory Postsynaptic Potential
Pathways		Iron uptake and transport
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		69 interacting genes: ADAMTSL4 ALKBH3 BCL6 BOLA1 CA9 CBLB CCHCR1 CGGBP1 CIAPIN1 EFEMP2 FAM118A FRA10AC1 GATA1 GMCL1 GRN HEXD IHO1 IKZF1 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE2D LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI MOXD1 NADK NOTCH2NLA OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ PRKD2 RGS20 SOX7 STAU1 TCF4 TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF148 ZNF23 ZNF426 ZNF512B ZNF544	4 interacting genes: ATXN1L GLRX3 NLRX1 RABGGTB
Entrez ID		10539	84866
HPRD ID		10153	11635
Ensembl ID		ENSG00000108010	ENSG00000149582
Uniprot IDs		A0A140VJK1 O76003	A0A024R3G8 B7Z1M8 E9PKP3 Q86YD3
PDB IDs		2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?
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