GLRX3 and KRT38

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GLRX3	KRT38
Description		glutaredoxin 3	keratin 38
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytosol Cell Cortex Z Disc Dendrite	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	RNA Binding Protein Kinase C Binding Protein Binding Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding	Structural Molecule Activity Protein Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Cellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy Electron Transport Chain [2Fe-2S] Cluster Assembly Cell Redox Homeostasis Protein Maturation By Iron-sulfur Cluster Transfer	Keratinization Cornification
Pathways		Iron uptake and transport	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		69 interacting genes: ADAMTSL4 ALKBH3 BCL6 BOLA1 CA9 CBLB CCHCR1 CGGBP1 CIAPIN1 EFEMP2 FAM118A FRA10AC1 GATA1 GMCL1 GRN HEXD IHO1 IKZF1 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE2D LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI MOXD1 NADK NOTCH2NLA OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ PRKD2 RGS20 SOX7 STAU1 TCF4 TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF148 ZNF23 ZNF426 ZNF512B ZNF544	46 interacting genes: AMOTL2 ANKRD36BP1 BEX2 C19orf57 C1orf216 CCDC146 CD300A CEP57L1 FAM90A1 GLRX3 GNG10 HAUS1 HDAC4 HGS HMG20B HOXA1 KDM1A KLHL38 KRT2 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT79 KRT8 KRT81 KRT83 LHX4 MAGEB4 PIK3R2 PIN1 PSMA1 PSMC5 PTGER3 RHPN1-AS1 SCNM1 TXLNA TXLNB TXNDC5 USHBP1 ZFYVE21 ZNF20 ZNF417 ZNF587
Entrez ID		10539	8687
HPRD ID		10153	05176
Ensembl ID		ENSG00000108010	ENSG00000171360
Uniprot IDs		A0A140VJK1 O76003	O76015
PDB IDs		2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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