GLRX3 and UGP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GLRX3	UGP2
Description		glutaredoxin 3	UDP-glucose pyrophosphorylase 2
Image
GO Annotations	Cellular Component	Cell Nucleus Cytosol Cell Cortex Z Disc Dendrite	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Binding Protein Kinase C Binding Protein Binding Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding	UTP:glucose-1-phosphate Uridylyltransferase Activity Protein Binding Glucose Binding Pyrimidine Ribonucleotide Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Cellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy Electron Transport Chain [2Fe-2S] Cluster Assembly Cell Redox Homeostasis Protein Maturation By Iron-sulfur Cluster Transfer	Glycogen Metabolic Process Glycogen Biosynthetic Process UDP-glucose Metabolic Process UDP-glucuronate Biosynthetic Process Glucose 1-phosphate Metabolic Process
Pathways		Iron uptake and transport	Formation of the active cofactor, UDP-glucuronate Glycogen synthesis
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)	Clozapine-induced agranulocytosis ( 25187353) Smoking initiation (ever regular vs never regular) ( 30679032) Systolic blood pressure ( 26969751)
Interacting Genes		69 interacting genes: ADAMTSL4 ALKBH3 BCL6 BOLA1 CA9 CBLB CCHCR1 CGGBP1 CIAPIN1 EFEMP2 FAM118A FRA10AC1 GATA1 GMCL1 GRN HEXD IHO1 IKZF1 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE2D LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI MOXD1 NADK NOTCH2NLA OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ PRKD2 RGS20 SOX7 STAU1 TCF4 TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF148 ZNF23 ZNF426 ZNF512B ZNF544	5 interacting genes: ABCA1 ARIH2 CBS GLRX3 PCBP1
Entrez ID		10539	7360
HPRD ID		10153	08934
Ensembl ID		ENSG00000108010	ENSG00000169764
Uniprot IDs		A0A140VJK1 O76003	A0A140VKE1 Q16851
PDB IDs		2DIY 2WZ9 2YAN 3ZYW	3R2W 3R3I 4R7P
Enriched GO Terms of Interacting Partners?
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