HMG20A and ADD1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HMG20A	ADD1
Description		high mobility group 20A	adducin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cell Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion F-actin Capping Protein Complex Postsynaptic Density Nuclear Body Plasma Membrane Raft
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding	RNA Binding Actin Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Calmodulin Binding Transcription Factor Binding Spectrin Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation	Cell Morphogenesis In Utero Embryonic Development Cell Volume Homeostasis Hemoglobin Metabolic Process Actin Cytoskeleton Organization Erythrocyte Differentiation Positive Regulation Of Protein Binding Multicellular Organism Growth IRE1-mediated Unfolded Protein Response Homeostasis Of Number Of Cells Within A Tissue Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Transmembrane Transport Cellular Response To Calcium Ion Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Adherens Junction Organization
Pathways			Caspase-mediated cleavage of cytoskeletal proteins XBP1(S) activates chaperone genes Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 30718926 28869590)	Household income ( 31844048) Household income (MTAG) ( 31844048) Huntington's disease progression ( 28642124)
Interacting Genes		25 interacting genes: ADD1 BRAP CCDC136 CCNK CFAP53 DCTN4 DTNA DTNB FBXO7 FMNL1 GTF2A1L HMG20B HPCAL1 KPNA2 MAGOHB PHF21A PSTPIP1 PTH2R RBM7 RPP30 RSPH9 SCNM1 SMAD4 SYTL4 TESC	21 interacting genes: ADD2 ATP1A1 CALM1 CASP3 CSNK2B GEMIN7 HMG20A HSPH1 ID2 ID3 MAP1LC3B PRKACA PRKCA PRKCD RFX1 ROCK1 SMARCC1 SPTA1 SPTB TK1 ZDHHC17
Entrez ID		10363	118
HPRD ID		16116	00036
Ensembl ID		ENSG00000140382	ENSG00000087274
Uniprot IDs		B4DMG1 Q9NP66	P35611
PDB IDs
Enriched GO Terms of Interacting Partners?
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